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High quality Isoniazid CAS NO.54-85-3
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Keywords
- 54-85-3
- Isoniazid
- Isoniazid price
Quick Details
- ProName: High quality Isoniazid
- CasNo: 54-85-3
- Molecular Formula: C6H7N3O
- Appearance: White or almost white crystalline powd...
- Application: antibacterial, tuberculostatic
- DeliveryTime: Within 3-32 days after payment confirm...
- PackAge: 25kg fiber drum
- Port: Shanghai
- Purity: 99%
- Storage: stored in cool and ventilated place
- Transportation: By air/sea
- LimitNum: 0
Superiority
1) Same day of payment provide Tracking Number of Fedex/DHL/EMS and within 4 days Delivery
2) Gauranteed Delivery
3) Reshipping Provided
4) No custom Problem
47) Better price and quality more than other suppliers as we have very good factpry supporting
Details
1.Product description
Product Name: Isoniazid
CAS: 54-85-3
MF: C6H7N3O
MW: 137.14
EINECS: 200-214-6
2.Physical properties
White crystalline powder
mp 171-173 °C(lit.)
Fp >250°C
storage temp. Refrigerator
Water Solubility 14 g/100 mL (25 oC)
Sensitive Air Sensitive
Merck 14,5186
BRN 119374
Stability: Stability Stable, but may be air or light sensitive. Combustible. Incompatible with strong oxidizing agents, chloral, aldehydes, iodine, ferric salts, hypochlorites.
3.Specification
Test Item
Analysis Specification
Result
Description
crystalline powder
Conforms
Melting range
129°C~132°C
130.8°C-131°C
Loss on drying
≤0.5%
0.20 %
Specific rotation
-58°~-62°(C=1,in CH3OH)
-61.05°
Sulphated ash
≤0.1%
0.08 %
Heavy metals
≤10ppm
Conforms
Chlorides
≤0.02%
Conforms
Sulfates
≤0.02%
Conforms
Fluorine
14.7%~17.9%
15.2%
Residual solvent
Methanol ≤0.2%
Isopropanol ≤0.2%
Ethyl acetate≤0.2%
Chloroform ≤0.2%
0.0%
0.0%
0.0%
0.0%
Related substances
(HPLC)
Single impurity ≤0.2%
Total impurities ≤0.5%
0.05%
0.08%
Assay
≥99.5%
99.92%
Conclusion
Accordance with the reference
4.Application
antibacterial, tuberculostatic
Antibiotic for treatment of Mycobacterium tuberculosis, inhibits mycolic acid biosynthesis. Metabolized by hepatic N-acetyltransferase (NAT) and cytochrome P450 2E1 (CYP2E1) to form hepatotoxins. Sele ctively induces expression of CYP2E1. Reversibly inhibits CYP2C19 and CYP3A4 activities, and mechanistically inactivates CYP1A2, CYP2A6, CYP2C19 and CYP3A4 at clinically relevant concentrations. Antib acterial (tuberculostatic).
For the treatment of all forms of tuberculosis in which organisms are susceptible.
Product Name: Isoniazid
CAS: 54-85-3
MF: C6H7N3O
MW: 137.14
EINECS: 200-214-6
2.Physical properties
White crystalline powder
mp 171-173 °C(lit.)
Fp >250°C
storage temp. Refrigerator
Water Solubility 14 g/100 mL (25 oC)
Sensitive Air Sensitive
Merck 14,5186
BRN 119374
Stability: Stability Stable, but may be air or light sensitive. Combustible. Incompatible with strong oxidizing agents, chloral, aldehydes, iodine, ferric salts, hypochlorites.
3.Specification
Test Item
Analysis Specification
Result
Description
crystalline powder
Conforms
Melting range
129°C~132°C
130.8°C-131°C
Loss on drying
≤0.5%
0.20 %
Specific rotation
-58°~-62°(C=1,in CH3OH)
-61.05°
Sulphated ash
≤0.1%
0.08 %
Heavy metals
≤10ppm
Conforms
Chlorides
≤0.02%
Conforms
Sulfates
≤0.02%
Conforms
Fluorine
14.7%~17.9%
15.2%
Residual solvent
Methanol ≤0.2%
Isopropanol ≤0.2%
Ethyl acetate≤0.2%
Chloroform ≤0.2%
0.0%
0.0%
0.0%
0.0%
Related substances
(HPLC)
Single impurity ≤0.2%
Total impurities ≤0.5%
0.05%
0.08%
Assay
≥99.5%
99.92%
Conclusion
Accordance with the reference
4.Application
antibacterial, tuberculostatic
Antibiotic for treatment of Mycobacterium tuberculosis, inhibits mycolic acid biosynthesis. Metabolized by hepatic N-acetyltransferase (NAT) and cytochrome P450 2E1 (CYP2E1) to form hepatotoxins. Sele ctively induces expression of CYP2E1. Reversibly inhibits CYP2C19 and CYP3A4 activities, and mechanistically inactivates CYP1A2, CYP2A6, CYP2C19 and CYP3A4 at clinically relevant concentrations. Antib acterial (tuberculostatic).
For the treatment of all forms of tuberculosis in which organisms are susceptible.
