Paroxetine hydrochloride/hcl CAS NO.78246-49-8

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1.Product description
Product Name: Paroxetine hydrochloride
CAS: 78246-49-8
MF: C19H21ClFNO3
MW: 365.83

2.Physical properties
Paroxetine hydrochloride is an odorless, off-white powder, having a melting point range of 120° to 138°C and a solubility of 5.4 mg/mL in water.

3.Specification
Appearance:White or almost white crystalline powder
Identification
A. Comparing with the spectrum obtained with CRS
Conform
B. The principal peak obtained with the test solution is similar in retention and size to that obtained with the reference solution
Conform
C. Water (by KF)
Conform
D. Reaction of chlorides
Conform
Impurity D≤0.2%

Related substances
1) Impurity A: not more than 0.3% :0.03%
2) Unspecified impurities: For each impurity, not more than 0.10 %
3) Total impurities: not more than 0.5%

Heavy metals≤0.002%
Water:2.2%~2.7%
Sulfated ash:≤0.1%
Assay(anhydrous substance):97.5%~102.0%
Residual solvents:Meets the requirements

4.Application
Paroxetine Hcl is primarily used to treat major depression, obsessive-compulsive disorder (OCD), Post-
traumatic stress disorder (PTSD). etc. It was first antidepressant formally approved in the US for treatment of
panic attacks

5.Packing
25KG/Drum or as per your requirement